A promising probiotic capable to reduce the impact of undernutrition on the development of sarcopenia
Résumé
Sarcopenia, worsened by malnutrition, represents ~20% of humans ≥ 60 years and increases risks of falls and dependency of older adults. Protein/energy-based supplementations remain not optimal to maintain muscle mass and function especially if targeted population is with poor appetite. Hence, complementary strategies independent of increased food intake have to be developed to limit sarcopenia.
We have shown that very atypical gut microbiota in small intestine-resected patients (i.e., 90% Lactobacilli), when transferred to axenic rats, could optimize the use of dietary nutrients and metabolism. We hypothesized that bacteria from this specific microbiota could be of interest to improve nutrients handling in older adults and limit sarcopenia.
Domaines
Alimentation et Nutrition
Origine : Fichiers produits par l'(les) auteur(s)