Article Dans Une Revue International Blood Research & Reviews Année : 2023

Hematological Profile of Adult Haemoglobin SS and SC Sickle Cell Patients in Stationary Phase: Evidences from National Teaching Hospital of Cotonou in Benin

T. Baglo-Agbodande
  • Fonction : Auteur
B. Houssou
  • Fonction : Auteur
R. Massi
  • Fonction : Auteur
E. Kassehin
  • Fonction : Auteur
G G Orou Guiwa
  • Fonction : Auteur
J. Dèhoumon
  • Fonction : Auteur
J. Mehou
  • Fonction : Auteur
L. Anani
  • Fonction : Auteur
A. Vovor
  • Fonction : Auteur
D. Kinde-Gazard
  • Fonction : Auteur

Résumé

Background and Objective: Sickle cell disease is a major public health problem. The aim of this study was to determine the hematological parameters in the inter-critical period of adult sickle cell patients at the National Teaching Hospital CNHU-HKM of Cotonou. Materials and Methods: This is a descriptive study with analytical aims carried out from July 2021 to December 2021 in the hematology department of the National Teaching Hospital CNHU-HKM of Cotonou. An hemogram was performed using Sysmex XT 4000i on a total of 181 sickle cell patients including 119 Hb SS and 62 Hb SC. Data were analyzed using R software. Results: Patients studied had a mean age of 32 ± 13 years. The mean of hemoglobin level was 7.7 ± 1.9 g/dL in Hb SS patients versus 11.27 ± 1.79 g/dL in Hb SC patients (p = 0.001). The mean leukocyte count was 13.2 ± 4.4 G/L in Hb SS patients versus 7.3 ± 3 G/L in Hb SC patients (p = 0.003); the mean neutrophil count was 6.93 ± 3.24 G/L in Hb SS patients versus 3.96 ± 1.72 G/L in Hb SC patients (p = 0.001). Platelet counts averaged 426 ± 213 G/L in Hb SS patients versus 223 ± 103 G/L in Hb SC patients (p = 0.001). Conclusion: This study revealed a higher mean hemoglobin level, mean leukocyte count and mean platelet count in Hb SS patients compared to Hb SC patients in the stationary phase.

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hal-04194475 , version 1 (03-09-2023)

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A. Zohoun, T. Baglo-Agbodande, B. Houssou, R. Massi, E. Kassehin, et al.. Hematological Profile of Adult Haemoglobin SS and SC Sickle Cell Patients in Stationary Phase: Evidences from National Teaching Hospital of Cotonou in Benin. International Blood Research & Reviews, 2023, 14 (4), pp.70-76. ⟨10.9734/ibrr/2023/v14i4319⟩. ⟨hal-04194475⟩
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