The motor burst of saccade-related neurons in the deep superior colliculus during interceptive saccades
Résumé
Neurons in the deep layers of the superior colliculus (dSC) emit a vigorous burst of action potentials during saccades toward a stationary target. A traditionally defined movement field identifies an optimal saccadic vector for which the neural discharge is maximal, and the level of activity decreases for saccades gradually deviated from this optimum. Neurons in the dSC also produce a burst during interceptive saccades made to foveally acquire a moving target. Keller et al. (1996) described peri-saccadic bursts during interceptive saccades aimed at targets that moved away from the initial fixation point and through the neuron's response field at a constant velocity (ususally 60 deg/sec). Two salient observations were reported: 1) the dSC's movement field center was shifted towards larger amplitude saccades relative to the center of movement fields collected using stationary targets; 2) the peak discharge for interceptive saccades tended to be lower than for saccades to stationary targets. To further characterize the apparent discrepancy in the bursts for saccades to stationary and moving targets, we recorded activity of dSC neurons in three head-restrained rhesus monkeys trained to produced interceptive saccades toward targets traveling in numerous paths and at various speeds. In all cases, the target travelled through the neuron's traditionally-defined movement field. Consistent with Keller and colleagues, we observed less vigorous peri-saccadic bursts during interceptive saccades, and this attenuation is associated with a reduction in peak velocity. However, we did not observe a robust shift in the movement field's optimal vector or boundaries for the slower target speeds used in our experiments. Furthermore, if a shift did occur, it was not always symmetrical for targets moving towards or away from the center of the traditional movement field. These data demonstrate that dSC is involved in the generation of interceptive saccades to moving targets. Further analyses are required to confidently decipher whether and how target motion-related signals contribute to the burst.
Domaines
Neurosciences [q-bio.NC]Origine | Fichiers produits par l'(les) auteur(s) |
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