Microstructured Magnetoelastic Membrane for Magnetic Bioactuators and Soft Artificial Muscles Applications
Résumé
In the growing field of mechanobiology, artificial mechano-reactive systems play
an essential role in the generation of mechanical forces and control of material
deformations. Free-standing magnetic nanoparticles have been studied for the
mechanical stimulation of living cells. Magnetic composite materials are also
used to mimic muscles at macroscale. In this study, a new magnetically actuated
membrane is focused, which can be used for various applications in soft robotics
or as a bioreactor. It consists of a few microns thick polydimethylsiloxane (PDMS)
membrane in which an array of magnetic microdisks is embedded. These
membranes have a large tuneable flexibility, and they are transparent, biocompatible,
and waterproof. They are usable in biology and optics, both
potentially combined. The membrane deformations under magnetic field have
been experimentally characterized and modeled. By growing pancreatic cells on
such membranes, it has been demonstrated that insulin production from the cells
can be enhanced thanks to the mechanical stimulation of the cells provided by
the actuated membrane.
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