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Article Dans Une Revue Pratique Neurologique - FMC Année : 2023

Practical treatment sheets for multiple sclerosis

Fiches pratiques thérapeutiques pour la prise en charge des patients atteints de sclérose en plaques

Résumé

Numerous immunotherapies are currently proposed for the treatment of patients with multiple sclerosis (MS). These are immunomodulative or immunosuppressive therapies, of different classes, which are planned to be used for the long term. Therefore neurologists must anticipate the specific risks of each treatment, the risk related to therapeutic switch, the risk of infection overtime, of teratogenicity and/or disease reactivation when stopping treatment in case of pregnancy plan while a therapeutic anti-inflammatory reactivity is important for the best prevention of chronical neurological damage. Faced with a patient with MS, the neurologist's mission is to take into account the different parameters that will guide the therapeutic decision (initiation or switch) and the required monitoring. We propose practical treatment sheets, combining characteristics of the different treatments, the recommendations of the French MS Society (Société francophone de la sclérose en plaques SF-SEP) (MS and vaccinations, infections, pregnancy), and their propositions when switching. We emphasize the importance of discussing complex individual situations with expert MS centers for the best management strategy.
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Dates et versions

hal-04163638 , version 1 (17-07-2023)

Identifiants

Citer

H. Zéphir, F. Durand-Dubief, E. Le Page. Fiches pratiques thérapeutiques pour la prise en charge des patients atteints de sclérose en plaques. Pratique Neurologique - FMC, 2023, 14 (2), pp.98-107. ⟨10.1016/j.praneu.2023.02.003⟩. ⟨hal-04163638⟩
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