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Article Dans Une Revue (Article De Synthèse) International Journal of Molecular Sciences Année : 2021

Liver Transplantation for Colorectal Liver Metastases: Current Management and Future Perspectives

Guillaume Rossignol
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Résumé

Patients with nonresectable liver metastases from colorectal cancer have few therapeutic options and a dismal prognosis. Although liver transplantation for this indication has historically a poor reputation, recent advances in the field of chemotherapy and immunosuppression have paved the way to revisit the concept. New data have shown promising results that need to be validated in several ongoing clinical trials. Since liver grafts represent a scarce resource, several new tools are being explored to expand the donor pool for this indication. The purpose of this review is to present all current available data and perspectives about liver transplantation for nonresectable liver metastases from colorectal cancer.
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Dates et versions

hal-04158388 , version 1 (11-07-2023)

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Serban Puia-Negulescu, Fanny Lebossé, Jean‐yves Mabrut, Xavier Muller, Guillaume Rossignol, et al.. Liver Transplantation for Colorectal Liver Metastases: Current Management and Future Perspectives. International Journal of Molecular Sciences, 2021, 22 (6), pp.3093. ⟨10.3390/ijms22063093⟩. ⟨hal-04158388⟩
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