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Article Dans Une Revue Infectious Diseases Now Année : 2023

Prospective cohort of COVID-19 patients requiring hospital admission in Douala, Cameroon

Résumé

OBJECTIVES: To report characteristics and outcome of COVID-19 patients who required hospital admission in sub-Saharan Africa clinics with no access to invasive mechanical ventilation. METHODS: Between April and June 2021, documented COVID-19 patients with SaO(2) <95% who were admitted in two clinics in Douala (Cameroon) were invited to participate. Data were prospectively collected using a standardized questionnaire. RESULTS: We included 67 patients: 39 males (58%), median age 62 years [50-70]. Comorbidities included hypertension (n=38, 57%), obesity (n=26, 38%), and diabetes (n=16, 24%). No patient reported COVID-19 vaccination. On admission, 35 patients (52%) required O(2) >6L/min. CT scan demonstrated extended lesions (>50%) in 50/61 cases (82%). Most patients received dexamethasone (n=64, 96%), heparin (n=64, 96%), chloroquine/azithromycin (n=59, 88%), and broad-spectrum antibiotics (n=59, 88%). Sixteen patients died (24%), after a median of 11.5 days [7.5-15.5] post-admission. CONCLUSIONS: Despite the lack of invasive mechanical ventilation, 76% of COVID-19 patients survived.
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hal-04089207 , version 1 (16-05-2023)

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Paternité - Pas d'utilisation commerciale

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S Tchamgoué, M Ntep Eboko, A Makamté, A Ngagnia, F Talla-Mba, et al.. Prospective cohort of COVID-19 patients requiring hospital admission in Douala, Cameroon. Infectious Diseases Now, 2023, 53 (5), pp.104713. ⟨10.1016/j.idnow.2023.104713⟩. ⟨hal-04089207⟩
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