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Article Dans Une Revue Hématologie Année : 2023

Dynamique moléculaire de la transformation des progéniteurs myéloïdes

Molecular dynamics of myeloid progenitor transformation

Résumé

Acute myeloid leukaemia (AML) is the most common acute leukaemia in adults. AML results from the accumulation of abnormal immature myeloid progenitors, also called blasts, that are blocked in their differentiation. AML is a very heterogeneous disease with more than a dozen of genetically distinct entities (See new AML classification from [1]). Each genetically distinct AML subgroup is generally defined by gene mutations and/or alterations related to its aggressiveness, and is associated to [...]

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Génétique
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Dates et versions

hal-04088289 , version 1 (04-05-2023)

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Marie-Laure Arcangeli, Frédéric Mazurier. Molecular dynamics of myeloid progenitor transformation. Hématologie, 2023, 29 (1), pp.24-25. ⟨10.1684/hma.2023.1783⟩. ⟨hal-04088289⟩
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