Methods for predicting the risk of developing pulmonary colonization/infection by pseudomonas aeruginosa - Archive ouverte HAL Accéder directement au contenu
Brevet Année : 2019

Methods for predicting the risk of developing pulmonary colonization/infection by pseudomonas aeruginosa

Résumé

The present invention relates to methods for predicting the risk of developing pulmonary colonization/infection by P. aeruginosa. The inventors analyzed the respiratory tract microbiota from 65 patients sputum samples and compared microbiota data. The inventors found that patients that will remain uninfected from P. aeruginosa exhibited 3-fold higher abundance of Porphyromonas catoniae compared to the other groups. In particular, the present invention relates to a method for predicting the risk of developing pulmonary colonization/infection by P. aeruginosa in a subject suffering from cystic fibrosis (CF) comprising measuring the abundance of Porphyromonas catoniae in a biological sample obtained from said subject.
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Dates et versions

hal-04084174 , version 1 (27-04-2023)

Identifiants

  • HAL Id : hal-04084174 , version 1

Citer

Patricia Lepage, Geneviève Hery-Arnaud, Jérôme Mounier, Charles-Antoine Guilloux, Stanislas Mondot, et al.. Methods for predicting the risk of developing pulmonary colonization/infection by pseudomonas aeruginosa. France, Patent n° : WO2019185778A1. 2019. ⟨hal-04084174⟩
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