The overall aims of the present investigation are to provide a detailed knowledge on the thermal turbulence statistics especially at the wall vicinity and to describe the thermal and rheological behaviour of the Non-Newtonian fluid, that in order to characterise the main features of the thermal turbulence and shed further light on the transfer mechanism of the turbulent energy. In addition to ascertain the accuracy and reliability of the present LES laboratory code by comparing the predicted findings with those available in the literature. Towards these purposes, a fully developed of the turbulent forced convection heat transfer of a thermally independent shear thinning (n=0.75) and Newtonian fluids in a heated pipe, has been carried out numerically by means of a Large eddy simulation (LES) with extended Smagorinsky model at simulation Reynolds and Prandtl numbers of 4000 and 1 respectively. The main findings suggest that the temperature fluctuations generation and the turbulent energy transport mechanism between the flow layers of the shear thinning fluid are pronounced compared to that of Newtonian fluid, the skewness and the flatness of the temperature fluctuations are almost independent of fluid flow index. Moreover, the present LES laboratory code can be considered as a powerful tool to resolve and predict the thermal turbulence statistics of such issue.