Rock slope failure (RSF) is now widely recognised as a significant contributor to the denudation of mountain ranges. Its spatial incidence can consequently be a valuable indicator of prevailing process domains, tectonic regimes and climatic variations, whether active or past. Here we provide the first systematic inventory of RSF in the Southern Carpathians, a mountain range marginally glaciated during the Pleistocene, cut by valleys up to 1.3 km deep, and displaying low-gradient summit erosion surfaces that suggest late Neogene uplift and incision of an extensive plateau. We discuss the spatial distribution of RSF in terms of process interactions and landscape evolution scenarios. Widespread metamorphic bedrock outcrops are confirmed as highly susceptible to RSF, particularly to large-scale slope deformation, but RSF also occurs on other lithologies as smaller rockslides and avalanches. Substantial spatial densities of RSF cluster around the residual, plateau-like range-top surface rims. We ascribe this to the ‘raised plateau’ features of the mountain range, where its fat, flat massifs engender greater slope stresses than would thin, serrated ones where arêtes and pyramidal peaks are gravitationally more stable. A large minority (42 %) of RSFs are spatially associated with glacial cirques and trough flanks. While these nominally qualify as paraglacial RSFs, glacial erosion may not be the main driver because the majority of RSFs occur along ridgetops and upper hillslopes in previously unglaciated fluvial contexts. Many of them thus qualify as parafluvial RSFs – i.e., occurring within a fluvial catchment but not directly generated by stream undercutting. We introduce the concept of fluvial–parafluvial and periglacial–parafluvial cycles as complementary to the recognised glacial–paraglacial cycle. All three process regimes may have prevailed concurrently or in succession, emphasising that cirque glaciation was probably not a principal agent in shrinking range-top erosion surfaces during the Quaternary. We point to post-orogenic (Neogene) tectonic uplift as the overarching driver of RSF in the Southern Carpathians, with pervasive fluvial incision keeping slopes close to failure thresholds. The role of RSF (extant and in earlier cycles) as a primary agent in perimeter scarp retreat and massif dissection here offers a ‘Transylvanian model’ of global interest whether as a comparator or a contrast for other ranges.