Water as Green Solvent: Methods of Solubilisation and Extraction of Natural Products—Past, Present and Future Solutions - Archive ouverte HAL
Article Dans Une Revue (Article De Synthèse) Pharmaceuticals Année : 2022

Water as Green Solvent: Methods of Solubilisation and Extraction of Natural Products—Past, Present and Future Solutions

Résumé

Water is considered the greenest solvent. Nonetheless, the water solubility of natural products is still an incredibly challenging issue. Indeed, it is nearly impossible to solubilize or to extract many natural products properly using solely water due to their low solubility in this solvent. To address this issue, researchers have tried for decades to tune water properties to enhance its solvent potential in order to be able to solubilise or extract low-water solubility compounds. A few methods involving the use of solubilisers were described in the early 2000s. Since then, and particularly in recent years, additional methods have been described as useful to ensure the effective green extraction but also solubilisation of natural products using water as a solvent. Notably, combinations of these green methods unlock even higher extraction performances. This review aims to present, compare and analyse all promising methods and their relevant combinations to extract natural products from bioresources with water as solvent enhanced by green solubilisers and/or processes.

Dates et versions

hal-04052040 , version 1 (30-03-2023)

Licence

Identifiants

Citer

Léo Lajoie, Anne-Sylvie Fabiano-Tixier, Farid Chemat. Water as Green Solvent: Methods of Solubilisation and Extraction of Natural Products—Past, Present and Future Solutions. Pharmaceuticals, 2022, 15 (12), pp.1507. ⟨10.3390/ph15121507⟩. ⟨hal-04052040⟩
21 Consultations
0 Téléchargements

Altmetric

Partager

More