This paper presents a Takagi-Sugeno (TS) fuzzy model-based controller for an interleaved DC-DC boost converter. Firstly, a TS model is developed using the bilinear model of the interleaved boost converter. Then, a TS fuzzy controller is designed to maintain the converter output voltage at the desired value with disturbance rejection. More precisely, the fuzzy controller gains are provided by solving a set of linear matrix inequalities (LMIs) based on the Lyapunov stability theory. These gains are used in the feedback control to determine the correct switch duty ratio to cause the converter output to reach the control objective even in the presence of load variations. Simulation results are given to show the applicability of the proposed control system for the interleaved DC-DC boost converter.