The purpose of this study is to investigate the efficacy of modified brick residues for the removal of well-known endocrine disrupting, 4-nonyl phenol (NP) and bisphenol A (BPA) from water. A better comprehension of the in-batch adsorption process was obtained by studying the effect of pH and temperature. The maximum of adsorption capacity was found at neutral pH. The adsorption kinetics, thermodynamics and isotherms modeling for NP and BPA were also investigated. The adsorption process followed Freundlich-type and pseudo-second-order kinetic (R2 > 0.99) with the adsorption capacity 94 and 92 mg/g, respectively, for NP and BPA which was among the highest values of BPA adsorption compared with other carbonaceous adsorbents according to the literature. The thermodynamic studies revealed that the adsorption process was fast and endothermic. The study of the adsorption performance in five consecutive cycles showed efficiencies higher than 90% in all cycles, revealing that the modified brick has good reusability. The results show that the modified brick residues as effective and efficient adsorbent material for the removal of NP and BPA from the water.