Zinc-Catalyzed Hydrocyanation of Ynamides and Photoisomerization, a General and Selective Access to E and Z Trisubstituted Alpha-Enamidonitriles - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Chemistry - A European Journal Année : 2023

Zinc-Catalyzed Hydrocyanation of Ynamides and Photoisomerization, a General and Selective Access to E and Z Trisubstituted Alpha-Enamidonitriles

Résumé

The fully regio and stereoselective Zn-catalyzed hydrocyanation of ynamides is reported and represents a general access to various trisubstituted E- alpha-enamidonitriles. The catalyst-free photoisomerization selectively yields the energetically comparable Z stereoisomer. Finally, the synthetic potential of these new !enamidonitriles was evaluated through the synthesis of original heterocycles.
Fichier principal
Vignette du fichier
Manuscript_HAL.pdf (700.08 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04051662 , version 1 (30-03-2023)

Identifiants

Citer

Pierre Hansjacob, Frédéric R Leroux, Morgan Donnard. Zinc-Catalyzed Hydrocyanation of Ynamides and Photoisomerization, a General and Selective Access to E and Z Trisubstituted Alpha-Enamidonitriles. Chemistry - A European Journal, 2023, pp.e202300120. ⟨10.1002/chem.202300120⟩. ⟨hal-04051662⟩
14 Consultations
5 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More