Early Prediction of All-Cause Clinical Deterioration in General Wards Patients: Development and Validation of a Biomarker-Based Machine Learning Model Derived From Rapid Response Team Activations - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Patient Safety Année : 2022

Early Prediction of All-Cause Clinical Deterioration in General Wards Patients: Development and Validation of a Biomarker-Based Machine Learning Model Derived From Rapid Response Team Activations

Résumé

Objective: The aim of the study is to evaluate the performance of a biomarker-based machine learning (ML) model (not including vital signs) derived from reviewed rapid response team (RRT) activations in predicting all-cause deterioration in general wards patients. Design: This is a retrospective single-institution study. All consecutive adult patients' cases on noncritical wards identified by RRT calls occurring at least 24 hours after patient admission, between April 2018 and June 2020, were included. The cases were reviewed and labeled for clinical deterioration by a multidisciplinary expert consensus panel. A supervised learning approach was adopted based on a set of biomarkers and demographic data available in the patient's electronic medical record (EMR). Setting: The setting is a 250-bed tertiary university hospital with a basic EMR, with adult (>18 y) patients on general wards. Patients: The study analyzed the cases of 514 patients for which the RRT was activated. Rapid response teams were extracted from the hospital telephone log data. Two hundred eighteen clinical deterioration cases were identified in these patients after expert chart review and complemented by 146 "nonevent" cases to build the training and validation data set.
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Dates et versions

hal-04013628 , version 1 (03-03-2023)

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Antoine Saab, Cynthia Abi Khalil, Mouin Jammal, Melody Saikali, Jean-Baptiste Lamy. Early Prediction of All-Cause Clinical Deterioration in General Wards Patients: Development and Validation of a Biomarker-Based Machine Learning Model Derived From Rapid Response Team Activations. Journal of Patient Safety, 2022, 18 (6), pp.578-586. ⟨10.1097/PTS.0000000000001069⟩. ⟨hal-04013628⟩
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