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Journal Articles Proceedings of the Nutrition Society Year : 1999

A genetic dissection of the retinoid signalling pathway in the mouse

Abstract

To determine the functions of retinoic acid receptors RAR and RXR, we have systematically knocked-out their genes by homologous recombination in the embryonic stem cells and generated null-mutant mice. This approach has allowed us to perform a genetic dissection of the retinoic acid signalling pathway.

Dates and versions

hal-03991565 , version 1 (15-02-2023)

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Manuel Mark, Norbert Ghyselinck, Olivia Wendling, Valérie Dupé, Bénédicte Mascrez, et al.. A genetic dissection of the retinoid signalling pathway in the mouse. Proceedings of the Nutrition Society, 1999, 58 (3), pp.609-613. ⟨10.1017/s0029665199000798⟩. ⟨hal-03991565⟩
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