Challenges and perspectives in MS-based omics approaches for ecotoxicology studies: An insight on Gammarids sentinel amphipods - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Frontiers in Analytical Science Année : 2023

Challenges and perspectives in MS-based omics approaches for ecotoxicology studies: An insight on Gammarids sentinel amphipods

Yohann Clément

Résumé

The aquatic environment is one of the most complex biosystems, as organism at all trophic levels may be exposed to a multitude of pollutants. As major goals, ecotoxicology typically investigates the impact of toxic pollutants on the ecosystems through the study of sentinel organisms. Over the past decades, Mass Spectrometry (MS)-based omics approaches have been extended to sentinel species both in laboratory and field exposure conditions. Single-omics approaches enable the discovery of biomarkers mirroring the health status of an organism. By covering a restricted set of the molecular cascade, they turn out to only partially satisfy the understanding of complex ecotoxicological effects. In contrast, a more complete understanding of the ecotoxicity pathways can be accessed through multi-omics approaches. In this perspective, we provide a state-of-the-art and a critical evaluation on further developments in MS-based single and multi-omics studies in aquatic ecotoxicology. As case example, literature regarding Gammarids freshwater amphipods, non-model sentinel organisms sensitive to pollutants and environmental changes and crucial species for downstream ecosystems, will be reviewed.
Fichier principal
Vignette du fichier
frans-03-1118494.pdf (936.49 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Licence : CC BY - Paternité

Dates et versions

hal-03986050 , version 1 (13-02-2023)

Licence

Paternité

Identifiants

Citer

Valentina Calabrese, Arnaud Salvador, Yohann Clément, Thomas Alexandre Brunet, Anabelle Espeyte, et al.. Challenges and perspectives in MS-based omics approaches for ecotoxicology studies: An insight on Gammarids sentinel amphipods. Frontiers in Analytical Science, 2023, 3, pp.1118494. ⟨10.3389/frans.2023.1118494⟩. ⟨hal-03986050⟩
48 Consultations
40 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More