Cerebellar degeneration in adult spinal muscular atrophy patients
Cerebellar degeneration in adult spinal muscular atrophy patients.
Résumé
Spinal muscular atrophy (SMA) is a genetic motor neuron disease related to deletions in the SMN1 gene. There is mounting evidence that the disease is not restricted to motor neurons. In this neuroimaging study, we aimed to investigate the presence of in-vivo cerebellar damage in adult SMA patients not treated with disease-modifying treatment.