Direct synthesis of functionalized 3-pyrrolidines and 4-piperidines using the borrowing hydrogen methodology
Résumé
The Ir(III)-catalyzed synthesis of 3-pyrrolidinols and 4-piperidinols combining 1,2,4-butanetriol or 1,3,5-pentanetriol with primary amines was carried out. This borrowing hydrogen methodology (BH) was further extended to the sequential diamination of triols leading to aza-pyrrolidines and aza-piperidines
Domaines
Chimie
Fichier principal
direct-synthesis-of-functionalized-3-pyrrolidines-and-4-piperidines-using-the-borrowing-hydrogen-methodology.pdf (484.06 Ko)
Télécharger le fichier
Origine | Fichiers produits par l'(les) auteur(s) |
---|---|
Licence |