Synthesis and biological evaluation of Fotemustine analogues on human melanoma cell lines - Archive ouverte HAL
Article Dans Une Revue European Journal of Medicinal Chemistry Année : 2003

Synthesis and biological evaluation of Fotemustine analogues on human melanoma cell lines

Résumé

Two new analogues of Fotemustine have been synthesized and tested on two melanoma cell lines. Compounds 4 and 8 proved to be more potent than the reference compound on A375 cell line which express the MGMT enzyme involved in the chemoresistance of tumoral cells.

Domaines

Chimie

Dates et versions

hal-03931124 , version 1 (09-01-2023)

Identifiants

Citer

Jean-Yves Winum, Jean-Luc Bouissière, Isabelle Passagne, Alexandre Evrard, Véronique Barragan-Montero, et al.. Synthesis and biological evaluation of Fotemustine analogues on human melanoma cell lines. European Journal of Medicinal Chemistry, 2003, 38 (3), pp.319-324. ⟨10.1016/s0223-5234(03)00014-x⟩. ⟨hal-03931124⟩

Collections

CNRS
25 Consultations
0 Téléchargements

Altmetric

Partager

More