Pulmonary vein isolation alone or in combination with substrate modulation after electrical cardioversion failure in patients with persistent atrial fibrillation: The PACIFIC trial: Study design - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Cardiovascular Electrophysiology Année : 2023

Pulmonary vein isolation alone or in combination with substrate modulation after electrical cardioversion failure in patients with persistent atrial fibrillation: The PACIFIC trial: Study design

Résumé

Pulmonary vein isolation (PVI) is effective at treating 50% of unselected patients with persistent atrial fibrillation (AF). Alternatively, PVI combined with a new ablation strategy entitled the Marshall-PLAN ensures a 78% 1-year sinus rhythm (SR) maintenance rate in the same population. However, a substantial subset of patients could undergo the Marshall-PLAN unnecessarily. It is therefore essential to identify those patients who can be treated with PVI alone versus those who may truly benefit from the Marshall-PLAN before ablation is performed. In this context, we hypothesized that electrical cardioversion (EC) could help to select the most appropriate strategy for each patient.
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Dates et versions

hal-03930936 , version 1 (17-01-2023)

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Agustin Alfonso Bortone, Eloi Marijon, Luca Rosario Limite, Philippe Lagrange, François Brigadeau, et al.. Pulmonary vein isolation alone or in combination with substrate modulation after electrical cardioversion failure in patients with persistent atrial fibrillation: The PACIFIC trial: Study design. Journal of Cardiovascular Electrophysiology, 2023, ⟨10.1111/jce.15761⟩. ⟨hal-03930936⟩
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