Effect of cell cycle arrest on intermediate metabolism in the marine diatom Phaeodactylum tricornutum
Résumé
Significance We examined the effect of cell cycle arrest in the diatom Phaeodactylum tricornutum. When the cycle is disrupted in G1 phase, it leads to unbalanced growth and the accumulation of storage products, especially lipids. In contrast to nitrogen-stressed cells, however, cells arrested in G1 do not cannibalize photosynthetic proteins and show little change in photosynthetic energy conversion efficiency. This study provides insight into how intermediate metabolism is scheduled with respect to the cell cycle in a marine diatom.