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Chapitre D'ouvrage Année : 2022

Geometric vascular singularities, hemodynamic markers and pathologies

Résumé

Vascular pathologies are numerous and varied, and their genesis and development are multifactorial. Nevertheless, it is now known that the characterization and analysis of the dynamics of fluids and structures involved in the functioning of certain segments of the vascular system allow their dysfunction to be better understood, and correlations to be established between these dynamics and the genesis and development of vascular pathologies. The purpose of this chapter is to describe flow behaviors in certain geometric singularities of the cardiovascular system, whether native or pathological, and to correlate their dynamics with the evolution of cardiovascular pathologies. These correlations can be made using associations between the spatiotemporal distributions of certain hemodynamic markers/indexes and in vivo observation of deleterious clinical events. Certain in silico and in vitro works conducted within the IRPHE Biomechanics team, mostly over the period of the “Biomechanics of fluids and transfers, biological structure-fluid interaction” and “MEChAnics of BIOlogical materials and fluids” research groups, will notably serve to illustrate the remarks, which will not necessarily be exhaustive.
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Dates et versions

hal-03859548 , version 1 (11-10-2023)

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  • HAL Id : hal-03859548 , version 1

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Valerie Deplano, Carine Guivier-Curien. Geometric vascular singularities, hemodynamic markers and pathologies. Valerie Deplano, Jose-Maria Fullana, Claude Verdier. Biological flow in large vessels; Dialog between numerical modeling and in vitro/in vivo experiment (250pages). Edition ISTE-WILEY. https://www.iste.co.uk/book.php?id=1883, ‎ Wiley-ISTE; 1er édition (1 juin 2022), 2022, ‎ 1789450659. ⟨hal-03859548⟩
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