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Journal Articles (Review Article) Current Opinion in Cell Biology Year : 2021

Mechanical plasticity in collective cell migration

Benoit Ladoux
René-Marc Mège


Collective cell migration is crucial to maintain epithelium integrity during developmental and repair processes. It requires a tight regulation of mechanical coordination between neighboring cells. This coordination embraces different features including mechanical self-propulsion of individual cells within cellular colonies and large-scale force transmission through cell-cell junctions. This review discusses how the plasticity of biomechanical interactions at cell-cell contacts could help cellular systems to perform coordinated motions and adapt to the properties of the external environment.
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hal-03859238 , version 1 (18-11-2022)



Shreyansh Jain, Benoit Ladoux, René-Marc Mège. Mechanical plasticity in collective cell migration. Current Opinion in Cell Biology, 2021, 72, pp.54-62. ⟨10.1016/⟩. ⟨hal-03859238⟩
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