X-Ray and Atomic Force Microscopy Structures of Short Chain Amphiphilic Cyclodextrins
Résumé
Cyclodextrins rendered amphiphilic by remarkably short substituents chains have been shown to form stable molecular layers1,2. The results deduced from compression isotherms of Langmuir films at the air-water interface led us to propose the formation of amphiphilic cyclodextrin multilayers and the existence of a highly rigid (solid) system. As the physical characteristics of the Langmuir films might be correlated with bulk solid-state structures, comparative crystallographic studies have been undertaken for α-, β- and γ-cyclodextrins selectively persubstituted at the primary face with very short hydrophobic groups.