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Article Dans Une Revue Journal of Perinatal Medicine Année : 2014

Short and medium-term outcomes of live-born twins after fetoscopic laser therapy for twin-twin transfusion syndrome

Résumé

OBJECTIVE: To evaluate short and medium term outcomes of children born of monochorionic pregnancies complicated by twin-twin transfusion syndrome treated by fetoscopic laser surgery. METHODS: This was a retrospective observational study performed between May 2007 and 2012. Neonatal data was from 45 patients under 5 years of age. The prospective observational study was of the neurologic outcome of these children using the Ages and Stages Questionnaire (ASQ), 2nd edition, French version, at up to 5 years of age. RESULTS: Neurologic assessment at discharge from maternity unit was normal for 41 infants (93.2%). Logistic regression suggested that the risk of neurosensory sequelae was significantly related to the status of donor [odds ratio=4.62 (1.18; 18.0)] and significantly preterm birth \textless32 weeks of gestation [odds ratio=5.50 (1.38; 21.9)]. Eleven questionnaires were considered abnormal (31.1%). Two children presented a severe neurologic abnormality (5.7%). There was no significant correlation between any area of the questionnaire and status at birth (donor or recipient). CONCLUSIONS: The data from our cohort, particularly as regards neurologic outcome, were satisfactory and concordant with previously published results. The use of the ASQ as a screening tool for neurologic outcome in children is original, which allowed in our cohort to highlight early neurological disorders.
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Dates et versions

hal-03828903 , version 1 (25-10-2022)

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Barthélémy Tosello, Julie Blanc, Jean-Baptiste Haumonté, Claude d'Ercole, Catherine Gire. Short and medium-term outcomes of live-born twins after fetoscopic laser therapy for twin-twin transfusion syndrome. Journal of Perinatal Medicine, 2014, 42 (1), pp.99--105. ⟨10.1515/jpm-2013-0119⟩. ⟨hal-03828903⟩
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