Abstract. The modulation of the winter impacts of Arctic sea-ice loss by the Pacific Decadal Oscillation (PDO) is investigated in the IPSL-CM6A-LR ocean–atmosphere general circulation model. Ensembles of simulations are performed with constrained sea-ice concentration following the Polar Amplification Model Intercomparison Project (PAMIP) and initial conditions sampling warm and cold phases of the PDO. Using a general linear model, we estimate the simulated winter impact of sea-ice loss, PDO and their combined effects. On the one hand, a negative North Atlantic Oscillation (NAO)-like pattern appears in response to sea-ice loss together with a modest deepening of the Aleutian Low. On the other hand, a warm PDO phase induces a large positive Pacific–North America pattern, as well as a small negative Arctic Oscillation pattern. Both sea-ice loss and warm PDO responses are associated with a weakening of the poleward flank of the eddy-driven jet, an intensification of the subtropical jet and a weakening of the stratospheric polar vortex. These effects are partly additive; the warm PDO phase therefore enhances the response to sea-ice loss, while the cold PDO phase reduces it. However, the effects of PDO and sea-ice loss are also partly non-additive, with the interaction between both signals being slightly destructive. This results in small damping of the PDO teleconnections under sea-ice loss conditions, especially in the stratosphere. The sea-ice loss responses are compared to those obtained with the same model in atmosphere-only simulations, where sea-ice loss does not significantly alter the stratospheric polar vortex.