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Article Dans Une Revue Science Translational Medicine Année : 2020

Inhibition of TET1 prevents the development of osteoarthritis and reveals the 5hmC landscape that orchestrates pathogenesis

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Modulating cytosine hydroxymethylation by inhibiting TET1 activity prevents osteoarthritis in mice.
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Piera Smeriglio, Fiorella Grandi, Spoorthi Davala, Venkata Masarapu, Pier Francesco Indelli, et al.. Inhibition of TET1 prevents the development of osteoarthritis and reveals the 5hmC landscape that orchestrates pathogenesis. Science Translational Medicine, 2020, 12 (539), ⟨10.1126/scitranslmed.aax2332⟩. ⟨hal-03815589⟩
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