We consider the quadratic semilinear wave equation in six dimensions. This energy critical problem admits a ground state solution, which is the unique (up to scaling) positive stationary solution. We prove that any spherically symmetric solution, that remains bounded in the energy norm, evolves asymptotically to a sum of decoupled modulated ground states, plus a radiation term. As a by-product of the approach we prove the non-existence of multisoliton solutions that do not emit any radiation. The proof follows the method initiated for large odd dimensions by the last three authors, reducing the problem to ruling out the existence of such non-radiative multisolitons, by deriving a contradiction from a finite dimensional system of ordinary differential equations governing their modulation parameters. In comparison, the difficulty in six dimensions is the failure of certain channel of energy estimates and the related existence of a linear resonance. The main novelties are the obtention of new channel of energy estimates, as well as the classification of non-radiative solutions with small energy.