European and global regulations on greenhouse gases are constantly evolving. Most of the fluorinated refrigerants currently used are close to be banned due to their high global warming potentials. Therefore new alternatives less harmful to the environment need to be developed. Our goal is to identify new natural refrigerant/absorbent pairs for an absorption refrigeration process. To limit the environmental impact of the working fluid pairs used, the natural refrigerant will be carbon dioxide and the absorbent will be a compound derived from biomass. This work presents the developed methodology to select potential biobased solvent to be used with CO2 in an absorption refrigeration process.