A community-based intervention to decrease the prevalence of HIV viremia among people who inject drugs in Vietnam - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue The Lancet Regional Health - Western Pacific Année : 2022

A community-based intervention to decrease the prevalence of HIV viremia among people who inject drugs in Vietnam

Huong Duong Thi
Pham Minh Khue
Hoang Thi Giang
Vinh Vu Hai
Oanh Thi Hai Khuat
  • Fonction : Auteur
Thanh Tuyet Thi Nham
  • Fonction : Auteur
Don C. Des Jarlais

Résumé

Background In most low-to-middle-income countries, HIV control at the population level among people who inject drugs (PWID) remains a major challenge. We aimed to demonstrate that an innovative intervention can identify HIV-positive PWID in the community who are not treated efficiently, and get them treated efficiently. Methods Between 2016 and 2020, we implemented an intervention consisting of mass HIV screening of PWID using three annual respondent-driven sampling surveys (RDSS) and a post-intervention evaluation RDSS in community-based organisation (CBO) sites, coupled with peer support to facilitate/improve access to antiretroviral and methadone therapy in Haiphong, Vietnam. The primary outcome was the proportion of identified uncontrolled HIV-positive PWID who achieved viral control. We also estimated the potential effect of the intervention on the proportion of PWID with HIV RNA >1000 copies/mL among all PWID during the study period. Findings Over the three RDSS, 3150 different PWID were screened, i.e. two-thirds of the estimated population size. They all injected heroin, their median age was of 39 years, 95% were male, 26.5% were HIV-infected, and 78.6% of the latter had HIV RNA ≤1000 copies/mL. Among the 177 PWID identified with an unsuppressed viral load, 73 (41.2%) achieved viral suppression at the final visit. HIV viremia decreased from 7.2% at baseline to 2.9% at the final RDSS (p<0.001). Up to 42% of this observed reduction may be explained by the intervention, in the absence of any external intervention targeting PWID during the study period. Interpretation Mass community-based screening using RDSS coupled with CBO support is a powerful tool to rapidly identify untreated HIV-positive PWID and (re)link them to care.
Fichier principal
Vignette du fichier
10.1016-J.lanwpc.2022.100538.pdf (443.86 Ko) Télécharger le fichier
Origine : Publication financée par une institution
Licence : CC BY NC ND - Paternité - Pas d'utilisation commerciale - Pas de modification

Dates et versions

hal-03750414 , version 1 (12-08-2022)

Licence

Paternité - Pas d'utilisation commerciale - Pas de modification

Identifiants

Citer

Huong Duong Thi, Jean‐pierre Molès, Pham Minh Khue, Roselyne Vallo, Hoang Thi Giang, et al.. A community-based intervention to decrease the prevalence of HIV viremia among people who inject drugs in Vietnam. The Lancet Regional Health - Western Pacific, 2022, 27, pp.100538. ⟨10.1016/j.lanwpc.2022.100538⟩. ⟨hal-03750414⟩
29 Consultations
73 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More