International versus national growth charts for identifying small and large-for-gestational age newborns: A population-based study in 15 European countries - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue The Lancet Regional Health - Europe Année : 2021

International versus national growth charts for identifying small and large-for-gestational age newborns: A population-based study in 15 European countries

Résumé

Background: To inform the on-going debate about the use of universal prescriptive versus national intrauter-ine growth charts, we compared perinatal mortality for small and large-for-gestational-age (SGA/LGA) infants according to international and national charts in Europe. Methods: We classified singleton births from 33 to 42 weeks of gestation in 2010 and 2014 from 15 countries (N = 1,475,457) as SGA (birthweight <10th percentile) and LGA (>90th percentile) using the international Intergrowth-21st newborn standards and national charts based on the customised charts methodology. We computed sex-adjusted odds ratios (aOR) for stillbirth, neonatal and extended perinatal mortality by this classification using multilevel models. Findings: SGA and LGA prevalence using national charts were near 10% in all countries, but varied according to international charts with a north to south gradient (3.0% to 10.1% and 24.9% to 8.0%, respectively). Com-pared with appropriate for gestational age (AGA) infants by both charts, risk of perinatal mortality was increased for SGA by both charts (aOR[95% confidence interval (CI)]=6.1 [5.6-6.7]) and infants reclassified by international charts from SGA to AGA (2.7 [2.3-3.1]), but decreased for those reclassified from AGA to LGA (0.6 [0.4-0.7]). Results were similar for stillbirth and neonatal death. Interpretation: Using international instead of national charts in Europe could lead to growth restricted infants being reclassified as having normal growth, while infants with low risks of mortality could be reclassified as having excessive growth.
Fichier principal
Vignette du fichier
THELANCETDE-D-20-01363 - HAL version.pdf (1.01 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03713375 , version 1 (04-07-2022)

Identifiants

Citer

Alice Hocquette, Mélanie Durox, Rachael Wood, Kari Klungsøyr, Katarzyna Szamotulska, et al.. International versus national growth charts for identifying small and large-for-gestational age newborns: A population-based study in 15 European countries. The Lancet Regional Health - Europe, 2021, 8, pp.100167. ⟨10.1016/j.lanepe.2021.100167⟩. ⟨hal-03713375⟩
28 Consultations
22 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More