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Article Dans Une Revue Annals of Intensive Care Année : 2020

Transpulmonary pressures in obese and non-obese COVID-19 ARDS

Résumé

Data on respiratory mechanics of COVID-19 ARDS patients are scarce. Respiratory mechanics and response to positive expiratory pressure (PEEP) may be different in obese and non-obese patients. Methods We investigated esophageal pressure allowing determination of transpulmonary pressures (PL ) and elastances (EL) during a decremental PEEP trial from 20 to 6 cm H 2 O in a cohort of COVID-19 ARDS patients. Results Fifteen patients were investigated, 8 obese and 7 non-obese patients. PEEP ≥ 16 cm H 2 O for obese patients and PEEP ≥10 cm H 2 O for non-obese patients were necessary to obtain positive expiratory P L . Change of PEEP did not alter significantly ΔP L or elastances in obese patients. However, in non-obese patients lung EL and ΔP L increased significantly with PEEP increase. Chest wall EL was not affected by PEEP variations in both groups.
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Dates et versions

hal-03708119 , version 1 (19-03-2024)

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Paternité

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Mehdi Mezidi, Florence Daviet, Paul Chabert, Sami Hraiech, Laurent Bitker, et al.. Transpulmonary pressures in obese and non-obese COVID-19 ARDS. Annals of Intensive Care, 2020, 10 (1), pp.129. ⟨10.1186/s13613-020-00745-w⟩. ⟨hal-03708119⟩
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