Outcomes of elective left colectomy in renal-transplanted patients: a single-center case-control study (LECoRT study) - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue International Journal of Colorectal Disease Année : 2021

Outcomes of elective left colectomy in renal-transplanted patients: a single-center case-control study (LECoRT study)

Résumé

Purpose: Renal-transplanted patients are reported to have a high anastomotic leakage (AL) rate after colorectal surgery. We aimed to define AL-related morbidity and mortality rates after elective left colectomy in renal-transplanted patients. Methods: Data were prospectively collected between 2010 and 2015 from patients who underwent elective left colectomy with supra-peritoneal anastomosis in a single French referral hospital. We compared AL rate, and morbidity and mortality rates between renal-transplanted patients and controls. Results: We identified 120 patients who underwent elective left colectomy during the study period. We retrospectively divided this cohort into 20 (17%) kidney-transplanted recipients (KTR-group) and the remaining 100 patients comprised the control group (C-group). There were no significant differences in sex, age, ASA score, body mass index, history of abdominal surgery and benign/malignant disease ratio between the KTR-group and the C-group. The AL rate was approximately four times higher in the KTR-group versus the C-group (25% vs 7%, p = 0.028). Intra-abdominal septic complications (p = 0.0005) and reoperation rates (p = 0.025) were also higher in the KTR-group. The laparoscopic approach was performed less in the KTR-group (35% versus 93%, p < 0.0001). Conclusion: Renal transplantation was identified as a risk factor of AL following elective left colectomy, as well as increased intra-abdominal septic morbidity and higher reoperation rate. Further multicentric studies are required to identify potential independent risk factors of AL after colorectal surgery in these frail populations.
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Dates et versions

hal-03663854 , version 1 (10-05-2022)

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Citer

Thomas Bardol, Regis Souche, Diane Genet, Charlotte Ferrandis, Françoise Guillon, et al.. Outcomes of elective left colectomy in renal-transplanted patients: a single-center case-control study (LECoRT study). International Journal of Colorectal Disease, 2021, 36 (6), pp.1209-1219. ⟨10.1007/s00384-021-03860-7⟩. ⟨hal-03663854⟩

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