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Article Dans Une Revue Journal of Neuromuscular Diseases Année : 2024

IMPatienT: an Integrated web application to digitize, process and explore Multimodal PATIENt daTa

Résumé

Medical acts, such as imaging, generally lead to the production of several medical text reports that describe the relevant findings. Such processes induce multimodality in patient data by linking image data to free-text data and consequently, multimodal data have become central to drive research and improve diagnosis of patients. However, the exploitation of patient data is challenging as the ecosystem of available analysis tools is fragmented depending on the type of data (images, text, genetic sequences), the task to be performed (digitization, processing, exploration) and the domain of interest (clinical phenotype, histology…). To address the challenges, the analysis tools need to be integrated in a simple, comprehensive, and flexible platform. Here, we present IMPatienT (Integrated digital Multimodal PATIENt daTa), a free and open-source web application to digitize, process and explore multimodal patient data. IMPatienT has a modular architecture, including four components to: (i) create a standard vocabulary for a domain, (ii) digitize and process free-text data by mapping it to a set of standard terms, (iii) annotate images and perform image segmentation, and (iv) generate an automatic visualization dashboard to provide insight on the data and perform automatic diagnosis suggestions. Finally, we demonstrate the usefulness of IMPatienT on a corpus of 40 simulated muscle biopsy reports of congenital myopathy patients. IMPatienT is a platform to digitize, process and explore patient data that can handle image and free-text data. As it relies on a user-designed vocabulary, it can be adapted to fit any domain of research and can be used as a patient registry for exploratory data analysis (EDA). A demo instance of the application is available at https://impatient.lbgi.fr.
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Dates et versions

hal-03635350 , version 1 (08-04-2022)
hal-03635350 , version 2 (27-09-2022)
hal-03635350 , version 3 (17-06-2024)

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Corentin Meyer, Norma Romero, Teresinha Evangelista, Brunot Cadot, Jocelyn Laporte, et al.. IMPatienT: an Integrated web application to digitize, process and explore Multimodal PATIENt daTa. Journal of Neuromuscular Diseases, 2024, Online ahead of print. ⟨10.3233/JND-230085⟩. ⟨hal-03635350v3⟩
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