Rodents monitor their error in self-generated duration on a single trial basis - Archive ouverte HAL Access content directly
Journal Articles Proceedings of the National Academy of Sciences of the United States of America Year : 2022

Rodents monitor their error in self-generated duration on a single trial basis

Abstract

A fundamental question in neuroscience is what type of internal representation leads to complex, adaptive behavior. When faced with a deadline, individuals’ behavior suggests that they represent the mean and the uncertainty of an internal timer to make near-optimal, time-dependent decisions. Whether this ability relies on simple trial-and-error adjustments or whether it involves richer representations is unknown. Richer representations suggest a possibility of error monitoring, that is, the ability for an individual to assess its internal representation of the world and estimate discrepancy in the absence of external feedback. While rodents show timing behavior, whether they can represent and report temporal errors in their own produced duration on a single-trial basis is unknown. We designed a paradigm requiring rats to produce a target time interval and, subsequently, evaluate its error. Rats received a reward in a given location depending on the magnitude of their timing errors. During the test trials, rats had to choose a port corresponding to the error magnitude of their just-produced duration to receive a reward. High-choice accuracy demonstrates that rats kept track of the values of the timing variables on which they based their decision. Additionally, the rats kept a representation of the mapping between those timing values and the target value, as well as the history of the reinforcements. These findings demonstrate error-monitoring abilities in evaluating self-generated timing in rodents. Together, these findings suggest an explicit representation of produced duration and the possibility to evaluate its relation to the desired target duration.
Fichier principal
Vignette du fichier
kononowicz_et_al-pnas_revision_4.pdf (3.05 Mo) Télécharger le fichier
Origin Files produced by the author(s)

Dates and versions

hal-03587286 , version 1 (25-02-2022)

Identifiers

Cite

Tadeusz Władysław Kononowicz, Virginie van Wassenhove, Valérie Doyère. Rodents monitor their error in self-generated duration on a single trial basis. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (9), pp.e2108850119. ⟨10.1073/pnas.2108850119⟩. ⟨hal-03587286⟩
68 View
62 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More