Current practice and evolving concepts in septic shock resuscitation - Archive ouverte HAL
Article Dans Une Revue Intensive Care Medicine Année : 2022

Current practice and evolving concepts in septic shock resuscitation

1 Erasmus MC - Erasmus University Medical Center [Rotterdam]
2 CUMC - Columbia University Medical Center
3 NYU - New York University School of Medicine
4 UC - Pontificia Universidad Católica de Chile
5 Service médical des soins intensifs [CHU Raymond Poincaré]
6 UVSQ Santé - UFR Sciences de la santé Simone Veil
7 IRCCS Milan - Istituto Clinico Humanitas [Milan]
8 CHIREC - Centre Hospitalier Interrégional Edith Cavell
9 ULB - Université libre de Bruxelles
10 Facultad de Ciencias Médicas [La Plata]
11 University of Washington [Seattle]
12 Albert Einstein College of Medicine [New York]
13 AP-HP - Hôpital Antoine Béclère [Clamart]
14 Université Paris-Saclay
15 Service de Réanimation Médicale [CHRU Nancy]
16 DCAC - Défaillance Cardiovasculaire Aiguë et Chronique
17 Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
18 CARMAS - Groupe de recherche clinique CARMAS (Cardiovascular and Respiratory Manifestations of Acute lung injury and Sepsis)
19 Pôle des Cardiopathies Congénitales du Nouveau-Né à L'adulte - Centre Constitutif Cardiopathies Congénitales Complexes M3C, Groupe Hospitalier Paris Saint-Joseph, Hôpital Marie-Lannelongue, Inserm U999, Université Paris-Saclay
20 ICESI - Universidad Icesi
21 King‘s College London
22 NHS Foundation Trust [London]
23 PITT - University of Pittsburgh
24 UBC - University of British Columbia [Canada]
25 UKE - Universitaetsklinikum Hamburg-Eppendorf = University Medical Center Hamburg-Eppendorf [Hamburg]
26 UMCG - University Medical Center Groningen [Groningen]
27 University of Groningen [Groningen]
28 CESP - Centre de recherche en épidémiologie et santé des populations
29 Hôpital Ambroise Paré [AP-HP]
30 HUB-ULB - Hôpital Erasme = Erasmus Hospital = Erasmus Ziekenhuis
31 D'Or Institute for Research and Education,
Maurizio Cecconi

Résumé

Clinical and pathophysiological understanding of septic shock has progressed exponentially in the previous decades, translating into a steady decrease in septic shock-related morbidity and mortality. Even though large randomized, controlled trials have addressed fundamental aspects of septic shock resuscitation, many questions still exist. In this review, we will describe the current standards of septic shock resuscitation, but the emphasis will be placed on evolving concepts in different domains such as clinical resuscitation targets, adequate use of fluids and vasoactive drugs, refractory shock, and the use of extracorporeal therapies. Multiple research opportunities remain open, and collaborative endeavors should be performed to fill in these gaps.

Dates et versions

hal-03579489 , version 1 (18-02-2022)

Identifiants

Citer

Jan Bakker, Eduardo Kattan, Djillali Annane, Ricardo Castro, Maurizio Cecconi, et al.. Current practice and evolving concepts in septic shock resuscitation. Intensive Care Medicine, 2022, 48 (2), pp.148-163. ⟨10.1007/s00134-021-06595-9⟩. ⟨hal-03579489⟩
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