Rab3 proteins: key players in the control of exocytosis - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Trends in Neurosciences Année : 1994

Rab3 proteins: key players in the control of exocytosis

Résumé

Although some mechanistic aspects of exocytosis, such as fusion events, have been well documented by the technique of time-resolved membrane-capacitance measurement, it was only recently that new insights into the molecular mechanisms involved in the traffic of secretory vesicles were provided by the convergence of different lines of research. In this review Lledo et al. present some of the recent findings concerning small GTPases of the Rab3 subfamily which regulate hormone release, triggered by entry of Ca2+, in endocrine and neuroendocrine cells. In view of these new results, Rab proteins might be considered as candidates for inhibition or stimulation of specific steps involved in vesicle traffic.

Dates et versions

hal-03577145 , version 1 (16-02-2022)

Identifiants

Citer

Pierre-Marie Lledo, Ludger Johannes, Philippe Vernier, Robert Zorec, François Darchen, et al.. Rab3 proteins: key players in the control of exocytosis. Trends in Neurosciences, 1994, 17 (10), pp.426-432. ⟨10.1016/0166-2236(94)90017-5⟩. ⟨hal-03577145⟩
6 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More