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Chapitre D'ouvrage Année : 2021

How to rot: A role for TOR. Interplay between carbon catabolite repression and TOR signaling pathway

Résumé

Dead wood is mainly composed of cellulose and hemicellulose which are sugar polymers but also of lignin, a polymer of phenolic compounds. Wood is an ecological niche for lignocellulosic saprotrophic fungi which are able to degrade those polymers and use degradation products for their growth. The major component released from wood decay is glucose. In the model yeast Saccharomyces cerevisiae, a saprotrophic but not a lignocellulolytic fungus, glucose is more than a nutrient. It is also a signal molecule reprogramming cell physiology. This phenomenon, described as glucose-induced carbon catabolite repression occurs through signaling cascades interacting with the TOR signaling pathway. In filamentous soft-rot fungi, growing on lignocellulosic materials leads to carbon catabolite repression and involves the TOR signaling pathway in the regulation of this cellular program. White-rot fungi are able to use all woody components including lignin. A carbon catabolite repression program has also been depicted in those fungi. Key actors of this program can be identified in white-rot fungi including segments of a TOR signaling pathway. This review aims to summarize those interplays between carbon catabolite repression and TOR signaling pathway in these different fungi.
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Dates et versions

hal-03541617 , version 1 (24-01-2022)

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Citer

Delphine Noël, Duy Vuong Nguyen, Rodnay Sormani. How to rot: A role for TOR. Interplay between carbon catabolite repression and TOR signaling pathway. Wood Degradation and Ligninolytic Fungi, 99, Elsevier, pp.151-173, 2021, Advances in Botanical Research, ⟨10.1016/bs.abr.2021.05.002⟩. ⟨hal-03541617⟩
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