Click chemistry for block polysaccharides with dihydrazide and dioxyamine linkers - A review - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Carbohydrate Polymers Année : 2022

Click chemistry for block polysaccharides with dihydrazide and dioxyamine linkers - A review

Résumé

Engineered block polysaccharides is a relatively new class of biomacromolecules consisting of chemical assembly of separate block structures at the chain termini. In contrast to conventional, laterally substituted polysaccharide derivatives, the block arrangement allows for much higher preservation of inherent chain properties such as biodegradability and stimuli-responsive self-assembly, while at the same time inducing new macromolecular properties. Abundant, carbon neutral, and even recalcitrant biomass is an excellent source of blocks, opening for numerous new uses of biomass for a wide range of novel biomaterials. Among a limited range of methodologies available for block conjugation, bifunctional linkers allowing for oxyamine and hydrazide ‘click’ reactions have recently proven useful additions to the repertoire. This article focuses the chemistry and kinetics of these reactions. It also presents some new data with the aim to provide useful protocols and methods for general use towards new block polysaccharides.

Domaines

Polymères
Fichier principal
Vignette du fichier
Click chemistry for block polysaccharides.pdf (2.06 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03515520 , version 1 (06-01-2022)

Licence

Paternité - Pas d'utilisation commerciale - Partage selon les Conditions Initiales

Identifiants

Citer

Amalie Solberg, Ingrid V. Mo, Line A.-A. Omtvedt, Berit L. Strand, Finn L. Aachmann, et al.. Click chemistry for block polysaccharides with dihydrazide and dioxyamine linkers - A review. Carbohydrate Polymers, 2022, 278, pp.118840. ⟨10.1016/j.carbpol.2021.118840⟩. ⟨hal-03515520⟩

Collections

CNRS INC-CNRS LCPO
49 Consultations
225 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More