Rapid technological advances in artificial intelligence are creating opportunities for real-time algorithmic modulations of a person’s facial and vocal expressions, or ‘deep-fakes’. These developments raises unprecedented societal and ethical questions which, despite much recent public awareness, are still poorly understood from the point of view of moral psychology. We report here on an experimental ethics study conducted on a sample of N = 303 participants ( predominantly young, western and educated), who evaluated the acceptability of vignettes describing potential applications of expressive voice transformation technology. We found that vocal deep-fakes were generally well accepted in the population, notably in a therapeutic context and for emotions judged otherwise difficult to control, and surprisingly, even if the user lies to their interlocutors about using them. Unlike other emerging technologies like autonomous vehicles, there was no evidence of social dilemma in which one would e.g. accept for others what they resent for themselves. The only real obstacle to the massive deployment of vocal deep-fakes appears to be situations where they are applied to a speaker without their knowing, but even the acceptability of such situations was modulated by individual differences in moral values and attitude towards science-fiction. This article is part of the theme issue ‘Voice modulation: from origin and mechanism to social impact (Part II)’.