Iridium(III) Catalyzed Z-Selective Allylic Arylation of α-Fluoro But-1-enoic Acid Amides via β-F-Elimination in Water
Résumé
Allylic arylation of -fluoro but-1-enoic acid amides with arylboronic acids was carried out in water by comparing the cata-lytic activity of iridium(III) and rhodium (III). Ir(III) has shown a strong superiority over Rh(III) to give allyl-aryl coupling products with excellent stereoselectivity in favor of the Z isomer. The origin of high stereoselectivity is perhaps because of the a coordination of iridium Ir-N or Ir-O.
Domaines
ChimieOrigine | Fichiers produits par l'(les) auteur(s) |
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