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Article Dans Une Revue Psychiatry Research Année : 2021

Retinal ganglion cell dysfunction is correlated with disturbed visual cognition in schizophrenia patients with visual hallucinations

Résumé

Patients with schizophrenia have altered visual cognition and retinal functions. No studies have explored if retinal anomalies are related to visual cognition and the presence of visual hallucinations (VH). We explored functional responses of the retinal ganglion cells in schizophrenia patients with or without VH and conducted a neuropsychological evaluation to explore the links between cognition and retinal function. The VH+ group showed poorer visual cognition and we found correlations between the amplitudes of the P50 and the N95 waves and visual cognition. Our results provide arguments for a link between retinal dysfunction, impaired visual processing and VH in schizophrenia.
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hal-03402898 , version 1 (13-02-2023)

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Florent Bernardin, Thomas Schwitzer, Karine Angioi-Duprez, Anne Giersch, Fabienne Ligier, et al.. Retinal ganglion cell dysfunction is correlated with disturbed visual cognition in schizophrenia patients with visual hallucinations. Psychiatry Research, 2021, 298, pp.113780. ⟨10.1016/j.psychres.2021.113780⟩. ⟨hal-03402898⟩
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