PHARMACODYNAMICS OF FOENICULUM VULGARE AGAINST ULCER, INFLAMMATION, HEPATOTOXICITY AND NEPHROTOXICITY - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Animal and Plant Sciences (Pakistan) Année : 2021

PHARMACODYNAMICS OF FOENICULUM VULGARE AGAINST ULCER, INFLAMMATION, HEPATOTOXICITY AND NEPHROTOXICITY

M Tanveer
  • Fonction : Auteur
A Shehzad
M.S. Butt
  • Fonction : Auteur
M Shahid
  • Fonction : Auteur

Résumé

The proposed study was designed to assess the phytotherapic potential of locally cultivated fennel seeds against certain lifestyle associated disarrays. Fennel seed powder was subjected to conventional solvent extraction (CSE) and supercritical fluid extraction (SFE), followed by evaluation of health improving perspectives of fennel extracted phytoconstituents. The in vivo phase comprised of five studies with three groups in each based upon the diets i.e. control (D0), nutraceuticalCSE (D1), and nutraceuticalSFE (D2). The five studies included in the experiment were control, ulcerogenic, inflammatory, hepatotoxicity, and nephrotoxicity. NutraceuticalSFE showed highest decline in gastric juice volume, gastric juice acidity and ulcer index (63.54, 47.33, and 51.65%, respectively) followed by nutraceuticalCSE (41.09, 27.63, and 38.71%, respectively) in ulcerogenic study. Likewise, the maximum decline in paw edema was observed in inflammatory study, as 30.43% and 24.54%, in D2 and D1, respectively. For study IV, the maximum decline in ALT, ALP, AST and bilirubin value was recorded during hepatotoxic study among all other studies i.
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Dates et versions

hal-03383092 , version 1 (19-10-2021)

Identifiants

Citer

M Tanveer, A Shehzad, M.S. Butt, M Shahid. PHARMACODYNAMICS OF FOENICULUM VULGARE AGAINST ULCER, INFLAMMATION, HEPATOTOXICITY AND NEPHROTOXICITY. Journal of Animal and Plant Sciences (Pakistan), 2021, 31 (3), pp.841-853. ⟨10.36899/JAPS.2021.3.0274⟩. ⟨hal-03383092⟩
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