Occupational socioeconomic risk associations for head and neck cancer in Europe and South America: Individual participant data analysis of pooled case–control studies within the INHANCE Consortium - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Epidemiology and Community Health Année : 2021

Occupational socioeconomic risk associations for head and neck cancer in Europe and South America: Individual participant data analysis of pooled case–control studies within the INHANCE Consortium

1 University of Glasgow
2 IPA - Institute for Prevention and Occupational Medicine of the German Social Accident Insurance
3 Leibniz Institute for Prevention Research and Epidemiology - BIPS
4 1. LF UK / 1st Faculty of Medicine - 1. lékařská fakulta, Univerzita Karlova [Praha, Česká republika] = First Faculty of Medicine, Charles University [Prague, Czech Republic]
5 University of Athens Medical School [Athens]
6 Unipd - Università degli Studi di Padova = University of Padua
7 UNITO - Università degli studi di Torino = University of Turin
8 Trinity College Dublin
9 Cancer Registry of Norway
10 University of Aberdeen
11 HKU - The University of Hong Kong
12 L’Hospitalet de Llobregat [Barcelona, Spain]
13 CIRC - IARC - Centre International de Recherche contre le Cancer - International Agency for Research on Cancer
14 Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
15 Irset - Institut de recherche en santé, environnement et travail
16 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
17 CESP - Centre de recherche en épidémiologie et santé des populations
18 IGR - Institut Gustave Roussy
19 SBE - Service de biostatistique et d'épidémiologie
20 University of Heidelberg, Medical Faculty
21 Mount Sinai School of Medicine
22 UNIBO - Alma Mater Studiorum Università di Bologna = University of Bologna
23 Universitad de Buenos Aires = University of Buenos Aires [Argentina]
24 UFPel - Universidade Federal de Pelotas = Federal University of Pelotas
25 HCPA - Hospital de Clínicas de Porto Alegre
26 FIOCRUZ - Fundação Oswaldo Cruz / Oswaldo Cruz Foundation
27 USP - Universidade de São Paulo = University of São Paulo
28 University of Utah School of Medicine [Salt Lake City]
D.I. Conway
  • Fonction : Auteur correspondant
A. Ross
  • Fonction : Auteur
D. Serraino
  • Fonction : Auteur
C. Healy
  • Fonction : Auteur
L. Fernandez
  • Fonction : Auteur
M.P. Curado
  • Fonction : Auteur

Résumé

Background - The association between socioeconomic disadvantage (low education and/or income) and head and neck cancer is well established, with smoking and alcohol consumption explaining up to three-quarters of the risk. We aimed to investigate the nature of and explanations for head and neck cancer risk associated with occupational socioeconomic prestige (a perceptual measure of psychosocial status), occupational socioeconomic position and manual-work experience, and to assess the potential explanatory role of occupational exposures. Methods - Pooled analysis included 5818 patients with head and neck cancer (and 7326 control participants) from five studies in Europe and South America. Lifetime job histories were coded to: (1) occupational social prestige-Treiman's Standard International Occupational Prestige Scale (SIOPS); (2) occupational socioeconomic position-International Socio-Economic Index (ISEI); and (3) manual/non-manual jobs. Results - For the longest held job, adjusting for smoking, alcohol and nature of occupation, increased head and neck cancer risk estimates were observed for low SIOPS OR=1.88 (95% CI: 1.64 to 2.17), low ISEI OR=1.74 (95% CI: 1.51 to 1.99) and manual occupations OR=1.49 (95% CI: 1.35 to 1.64). Following mutual adjustment by socioeconomic exposures, risk associated with low SIOPS remained OR=1.59 (95% CI: 1.30 to 1.94). Conclusions - These findings indicate that low occupational socioeconomic prestige, position and manual work are associated with head and neck cancer, and such risks are only partly explained by smoking, alcohol and occupational exposures. Perceptual occupational psychosocial status (SIOPS) appears to be the strongest socioeconomic factor, relative to socioeconomic position and manual/non-manual work.
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Dates et versions

hal-03379703 , version 1 (30-05-2022)

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Paternité - Pas d'utilisation commerciale

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D.I. Conway, J. Hovanec, W. Ahrens, A. Ross, I. Holcatova, et al.. Occupational socioeconomic risk associations for head and neck cancer in Europe and South America: Individual participant data analysis of pooled case–control studies within the INHANCE Consortium. Journal of Epidemiology and Community Health, 2021, 75 (8), pp.779-787. ⟨10.1136/jech-2020-214913⟩. ⟨hal-03379703⟩
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