Tandem reactions of organnometallic reagents with a combined aminonitrile-oxazolidine system
Résumé
The reaction of the model combined aminonitrile-oxazolidine system I with a variety of Grignard and other organometallic reagents leads to the heterocyclic structures 3-imidazolines 2 and 2-aminomorpholines 3 by tandem addition/substitution reactions. The regioselectivity of the initial attack,
and hence the relative proportions of products, varies with the nature of the reagent and the presence of Lewis acidity in the mixture
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