RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay
Résumé
Purpose: Biological and/or physical assays for retrospective dosimetry are valuable tools to
recover the exposure situation and to aid medical decision making. To further validate and
improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed
a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios.
Materials and methods: For the dicentric chromosome assay (DCA), blood tubes were located at
anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36
TBq 192Ir-source. For each exposure condition, dose estimates were provided by at least one
laboratory and for four conditions by 17 participating RENEB laboratories. Three radio-photoluminescence
glass dosimeters were placed at each tube to assess reference doses.
Results: The DCA results were homogeneous between participants and matched well with the reference
doses ( 95% of estimates within ±0.5 Gy of the reference). For samples close to the source
systematic underestimation could be corrected by accounting for exposure time. Heterogeneity
within and between tubes was detected for reference doses as well as for DCA doses estimates.
Conclusions: The participants were able to successfully estimate the doses and to provide important
information on the exposure scenarios under conditions closely resembling a real-life situation.
Domaines
Sciences du Vivant [q-bio]| Origine | Fichiers éditeurs autorisés sur une archive ouverte |
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