RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue International Journal of Radiation Biology Année : 2021

RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay

Mirta Milic
  • Fonction : Auteur
  • PersonId : 1111346
Marco Valente
  • Fonction : Auteur
  • PersonId : 1111347
Laure Bobyk
  • Fonction : Auteur

Résumé

Purpose: Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. Materials and methods: For the dicentric chromosome assay (DCA), blood tubes were located at anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36 TBq 192Ir-source. For each exposure condition, dose estimates were provided by at least one laboratory and for four conditions by 17 participating RENEB laboratories. Three radio-photoluminescence glass dosimeters were placed at each tube to assess reference doses. Results: The DCA results were homogeneous between participants and matched well with the reference doses ( 95% of estimates within ±0.5 Gy of the reference). For samples close to the source systematic underestimation could be corrected by accounting for exposure time. Heterogeneity within and between tubes was detected for reference doses as well as for DCA doses estimates. Conclusions: The participants were able to successfully estimate the doses and to provide important information on the exposure scenarios under conditions closely resembling a real-life situation.
Fichier principal
Vignette du fichier
0000173474_001.PDF (17.74 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03354887 , version 1 (26-09-2021)

Identifiants

Citer

David Endesfelder, Ursula Oestreicher, Ulrike Kulka, Elizabeth Ainsbury, Jayne Moquet, et al.. RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay. International Journal of Radiation Biology, 2021, 97 (9), pp.1181 - 1198. ⟨10.1080/09553002.2021.1941380⟩. ⟨hal-03354887⟩
38 Consultations
15 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More