The extracellular matrix in pancreatic cancer: description of a complex network and promising therapeutic options
Résumé
Pancreatic ductal adenocarcinoma (PDAC) presents an abundant fibrotic stroma characterized by a stiff extracellular matrix (ECM) which is constantly remodeled to create a microenvironment promoting tumor growth and metastasis. The importance of stroma in driving and supporting PDAC progression is becoming clear as well as
Domaines
Sciences du Vivant [q-bio]
Origine : Fichiers produits par l'(les) auteur(s)